Protein Details: Glutamate receptor 3.1

Protein ID

ICDB_Pro_1169

Protein Name

Glutamate receptor 3.1

Gene Name

GLR3.1; ACL1; GLR2; At2g17260; F5J6.2

Organism

Arabidopsis thaliana (Mouse-ear cress)

Length

925 amino acids

AlphaFoldDB

AF-Q7XJL2-F1-model_v4.pdb

Function

Glutamate-gated receptor that probably acts as a non-selective cation channel. May be involved in light-signal transduction and calcium homeostasis via the regulation of calcium influx into cells. Required for the long-term calcium oscillation-regulated stomatal movements.

Sequence

MLSSMNWVLLSFIIVLGGGLLLSEGASSSRPPVIKVGAIFGLNTMYGETANIAFKAAEEDVNSDPSFLGGSKLRILMNDAKRSGFLSIMGALQFMETDVVAIIGPQTSIMAHVLSHLANELTVPMLSFTALDPTLSPLQFPFFVQTAPSDLFLMRAIAEMITYYGWSDVVALYNDDDNSRNGVTALGDELEERRCKISYKAVLPLDVVITSPVEIIEELIKIRGMESRVIVVNTFPNTGKMIFKEAERLGMMEKGYVWIATTWLSSVLDSNLPLDTKLVNGVLTLRLHTPDSRKKRDFAARWKNKLSNNKTIGLNVYGLYAYDTVWIIARAVKTLLEAGGNLSFSNDAKLGSLKGEALNLSALSRFDQGSQLLDYIVHTKMSGLTGPVQFHPDRSMLQPSYDIINLVDDRVHQIGYWSNYSGLSIVPPESFYSKPPNRSSSNQHLNSVTWPGGTSVTPRGWIFRNNGRRLRIGVPDRASFKDFVSRVNGSSNKVQGYCIDVFEAAVKLLSYPVPHEFIFFGDGLTNPNYNELVNKVTTGVDFDAVVGDIAIVTKRTRIVDFTQPYIESGLVVVAPVTRLNENPWAFLRPFTLPMWAVTASFFVIVGAAIWILEHRINDEFRGPPRRQIITILWFTFSTMFFSHRETTVSTLGRMVLLIWLFVVLIITSSYTASLTSILTVQQLNSPIKGVDTLISSTGRIGFQVGSFAENYMTDELNIASSRLVPLASPEEYANALQNGTVAAIVDERPYIDLFLSDYCKFAIRGQEFTRCGWGFAFPRDSPLAVDMSTAILGLSETGELQKIHDRWLSKSNCSSPHGSQSGDSEQLNVHSFWGMFLVVGIACLVALFIHFFKIIRDFCKDTPEVVVEEAIPSPKSSRLTKLQTFLAFVDEKEEETKRRLKRKRNNDHSMNANSIISRTASRRPI

PDB Structures

Ligand Binding

1. DICL_CP

2. DICL_Pep

Binding Site

Disease

Location

Expressed predominantly in roots. Firt detected in the vascular tissues of the cotyledons; and later in the vasculature of all organs. In leaves; preferentially expressed in guard cells. In leaves; preferentially expressed in guard cells. In leaves; preferentially expressed in guard cells.

DOI ID

10.1038/24066; 10.1111/j.1365-313x.2009.03789.x; 10.1038/45471; 10.1111/tpj.13415; 10.1126/science.292.5521.1486b; 10.1093/oxfordjournals.molbev.a004165

RefSeq

NP_001318239.1